The Role of Dupilumab in Severe Asthma

Dupilumab is a fully humanized monoclonal antibody, capable of inhibiting intracellular signaling of both interleukin (IL)-4 and IL-13. These are two molecules that, together with other proinflammatory cytokines such as IL-5 and eotaxins, play a pivotal role in orchestrating the airway inflammatory...

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Bibliographic Details
Main Authors: Fabio Luigi Massimo Ricciardolo, Francesca Bertolini, Vitina Carriero
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/9/9/1096