Sulfamethoxazole-induced crystal nephropathy: characterization and prognosis in a case series

Abstract Cotrimoxazole (Trimethoprim/Sulfamethoxazole-SMX) is frequently used in critically ill and immunocompromised patients. SMX is converted to N-acetyl-sulfamethoxazole (NASM) and excreted by the kidneys. NASM may form crystals in urine, especially in acid urine, that may induce a crystalline n...

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Bibliographic Details
Main Authors: Ruben Azencot, Camille Saint-Jacques, Jean-Philippe Haymann, Vincent Frochot, Michel Daudon, Emmanuel Letavernier
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-56322-9