Microglial Cytokines Induce Invasiveness and Proliferation of Human Glioblastoma through Pyk2 and FAK Activation

Microglial Cytokines Induce Invasiveness and Proliferation of Human Glioblastoma through Pyk2 and FAK Activation

Glioblastoma is the most aggressive brain tumor in adults. Multiple lines of evidence suggest that microglia create a microenvironment favoring glioma invasion and proliferation. Our previous studies and literature reports indicated the involvement of focal adhesion kinase (FAK) and proline-rich tyr...

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Bibliographic Details
Main Authors: Rebeca E. Nuñez, Miguel Mayol del Valle, Kyle Ortiz, Luis Almodovar, Lilia Kucheryavykh
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
glioblastoma
microglia
tumor microenvironment
Pyk2
FAK
invasion
Online Access:https://www.mdpi.com/2072-6694/13/24/6160

Internet

https://www.mdpi.com/2072-6694/13/24/6160

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