Temporal analysis of melanogenesis identifies fatty acid metabolism as key skin pigment regulator.

Therapeutic methods to modulate skin pigmentation has important implications for skin cancer prevention and for treating cutaneous hyperpigmentary conditions. Towards defining new potential targets, we followed temporal dynamics of melanogenesis using a cell-autonomous pigmentation model. Our study...

Full description

Bibliographic Details
Main Authors: Farina Sultan, Reelina Basu, Divya Murthy, Manisha Kochar, Kuldeep S Attri, Ayush Aggarwal, Pooja Kumari, Pooja Dnyane, Jyoti Tanwar, Rajender K Motiani, Archana Singh, Chetan Gadgil, Neel Sarovar Bhavesh, Pankaj K Singh, Vivek T Natarajan, Rajesh S Gokhale
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001634