Short-term genome stability of serial Clostridium difficile ribotype 027 isolates in an experimental gut model and recurrent human disease.

BACKGROUND:Clostridium difficile whole genome sequencing has the potential to identify related isolates, even among otherwise indistinguishable strains, but interpretation depends on understanding genomic variation within isolates and individuals. METHODS:Serial isolates from two scenarios were whol...

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Manylion Llyfryddiaeth
Prif Awduron: David W Eyre, A Sarah Walker, Jane Freeman, Simon D Baines, Warren N Fawley, Caroline H Chilton, David Griffiths, Alison Vaughan, Derrick W Crook, Tim E A Peto, Mark H Wilcox
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Public Library of Science (PLoS) 2013-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC3655144?pdf=render