Long-Read Sequencing Annotation of the Transcriptome in DNA-PK Inactivated Cells

Long-Read Sequencing Annotation of the Transcriptome in DNA-PK Inactivated Cells

The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) with a Ku70/Ku80 heterodimer constitutes the intact DNA-PK kinase, which is an upstream component of the DNA repair machinery that signals the DNA damage, orchestrates the DNA repair, and serves to maintain genome integrity. Beyond its ro...

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Bibliographic Details
Main Authors: Liwei Song, Mengjun Yu, Renjing Jin, Meng Gu, Ziyu Wang, Dailun Hou, Shaofa Xu, Jinghui Wang, Teng Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
long-read sequencing
DNA-PK
transcriptome
short-read sequencing
alternative splicing
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.941638/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.941638/full

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