Differential effects of glucose‐dependent insulinotropic polypeptide receptor/glucagon‐like peptide‐1 receptor heteromerization on cell signaling when expressed in HEK‐293 cells

Differential effects of glucose‐dependent insulinotropic polypeptide receptor/glucagon‐like peptide‐1 receptor heteromerization on cell signaling when expressed in HEK‐293 cells

Abstract The incretin hormones: glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1) are important regulators of many aspects of metabolism including insulin secretion. Their receptors (GIPR and GLP‐1R) are closely related members of the secretin class of G‐protein‐...

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Bibliographic Details
Main Authors: Bashaier Al‐Zaid, Siby Chacko, Charles Ifeamalume Ezeamuzie, Moritz Bünemann, Cornelius Krasel, Tina Karimian, Peter Lanzerstorfer, Suleiman Al‐Sabah
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Pharmacology Research & Perspectives
Subjects:
BRET4
FRET3
G‐protein‐coupled receptor1
GIP6
GLP‐15
heteromerization2
Online Access:https://doi.org/10.1002/prp2.1013

Internet

https://doi.org/10.1002/prp2.1013

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