Pathophysiology of ion channels in amyotrophic lateral sclerosis

Abstract Amyotrophic lateral sclerosis (ALS) stands as the most prevalent and severe form of motor neuron disease, affecting an estimated 2 in 100,000 individuals worldwide. It is characterized by the progressive loss of cortical, brainstem, and spinal motor neurons, ultimately resulting in muscle w...

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Bibliographic Details
Main Authors: Robin N. Stringer, Norbert Weiss
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-023-01070-6