Variable VlsE is critical for host reinfection by the Lyme disease spirochete.

Many pathogens make use of antigenic variation as a way to evade the host immune response. A key mechanism for immune evasion and persistent infection by the Lyme disease spirochete, Borrelia burgdorferi, is antigenic variation of the VlsE surface protein. Recombination results in changes in the Vls...

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Bibliographic Details
Main Authors: Artem S Rogovskyy, Troy Bankhead
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620393?pdf=render