The role behind the scenes of Tregs and Th17s in Hashimoto’s thyroiditis: Toward a pivotal role of FOXP3 and BACH2

The role behind the scenes of Tregs and Th17s in Hashimoto’s thyroiditis: Toward a pivotal role of FOXP3 and BACH2

In Hashimoto’s thyroiditis (HT), the genetic bases play a central role in determining development of the disease. In particular, the most frequent genes involved in the onset of HT are the Human Leukocyte Antigen (HLA). However, there are other genes and transcription factors in the autoimmune backg...

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Bibliographic Details
Main Authors: Alessio Mazzieri, Pia Montanucci, Giuseppe Basta, Riccardo Calafiore
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
Hashimoto’s thyroiditis
autoimmunity
imbalance Th17/Treg
BACH2
FOXP3
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1098243/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1098243/full

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