Differentiation-inducing factor 1 activates cofilin through pyridoxal phosphatase and AMP-activated protein kinase, resulting in mitochondrial fission
Differentiation-inducing factor 1 (DIF-1) is a morphogen produced by Dictyostelium discoideum that inhibits the proliferation and migration of both D. discoideum and most mammalian cells. Herein, we assessed the effect of DIF-1 on mitochondria, because DIF-3, which is similar to DIF-1, reportedly lo...
Main Authors: | Takeru Inoue, Koichi Miura, Ruzhe Han, Fumi Seto-Tetsuo, Masaki Arioka, Kazunobu Igawa, Katsuhiko Tomooka, Toshiyuki Sasaguri |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-05-01
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Series: | Journal of Pharmacological Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861323000117 |
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