Discovery of the Potentiator of the Pore-Forming Ability of Lantibiotic Nisin: Perspectives for Anticancer Therapy

Discovery of the Potentiator of the Pore-Forming Ability of Lantibiotic Nisin: Perspectives for Anticancer Therapy

This study was focused on the action of lantibiotic nisin on the phospholipid membranes. Nisin did not produce ion-permeable pores in the membranes composed of DOPC or DOPE. The introduction of DOPS into bilayer lipid composition led to a decrease in the threshold detergent concentration of nisin. A...

Full description

Bibliographic Details
Main Authors: Dayana N. Chernyshova, Alexander A. Tyulin, Olga S. Ostroumova, Svetlana S. Efimova
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Membranes
Subjects:
lantibiotic
nisin
ion channel
lipid bilayers
cardiolipin
membrane dipole potential
Online Access:https://www.mdpi.com/2077-0375/12/11/1166

Internet

https://www.mdpi.com/2077-0375/12/11/1166

Similar Items