Generation of 10 patient-specific induced pluripotent stem cells (iPSCs) to model Pitt-Hopkins Syndrome

Generation of 10 patient-specific induced pluripotent stem cells (iPSCs) to model Pitt-Hopkins Syndrome

Autosomal dominant mutations in transcription factor 4 (TCF4) are associated with a rare syndromic form of Autism Spectrum Disorder (ASD) called Pitt-Hopkins Syndrome (PTHS). Here, we report the generation of a collection of induced pluripotent stem cells (iPSCs) from 5 patients diagnosed with PTHS...

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Bibliographic Details
Main Authors: S.R. Sripathy, Y. Wang, R.L. Moses, A. Fatemi, D.A. Batista, B.J. Maher
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Stem Cell Research
Subjects:
Induced pluripotent stem cells (iPSCs)
Pitt-hopkins syndrome
Transcription factor 4 (TCF4)
Autism Spectrum Disorder (ASD)
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120303020

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http://www.sciencedirect.com/science/article/pii/S1873506120303020

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