Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection

Multi-targeted loss of the antigen presentation molecule MR1 during HSV-1 and HSV-2 infection

Summary: The major histocompatibility complex (MHC), Class-I-related (MR1) molecule presents microbiome-synthesized metabolites to Mucosal-associated invariant T (MAIT) cells, present at sites of herpes simplex virus (HSV) infection. During HSV type 1 (HSV-1) infection there is a profound and rapid...

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Bibliographic Details
Main Authors: Carolyn Samer, Hamish E.G. McWilliam, Brian P. McSharry, Thilaga Velusamy, James G. Burchfield, Richard J. Stanton, David C. Tscharke, Jamie Rossjohn, Jose A. Villadangos, Allison Abendroth, Barry Slobedman
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Cell biology
Immunology
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224000221

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http://www.sciencedirect.com/science/article/pii/S2589004224000221

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