A stability indicating UPLC method development and validation for the simultaneous estimation of nateglinide and metformin hydrochloride in bulk and tablet dosage form

A stability indicating UPLC method development and validation for the simultaneous estimation of nateglinide and metformin hydrochloride in bulk and tablet dosage form

Abstract Background Nateglinide and metformin HCl are used in combination for the treatment of type 2 diabetes. A simple, sensitive and reliable UPLC method was developed for simultaneous estimation of nateglinide and metformin HCl using Phenomenox C18 (50*2.1 mm, 3.5 µm) column at ambient temperatu...

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Bibliographic Details
Main Authors: Ashritha Narikimalli, Rajitha Galla
Format: Article
Language:English
Published: SpringerOpen 2023-06-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
UPLC
Method development
Validation
Forced degradation studies
Nateglinide
Metformin HCl
Online Access:https://doi.org/10.1186/s43094-023-00503-2

Internet

https://doi.org/10.1186/s43094-023-00503-2

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