Distribution and history of extensional stresses on vWF surrogate molecules in turbulent flow

Abstract The configuration of proteins is critical for their biochemical behavior. Mechanical stresses that act on them can affect their behavior leading to the development of decease. The von Willebrand factor (vWF) protein circulating with the blood loses its efficacy when it undergoes non-physiol...

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Bibliographic Details
Main Authors: Oanh L. Pham, Samuel E. Feher, Quoc T. Nguyen, Dimitrios V. Papavassiliou
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-04034-9