Interleukin-10 haplotypes are not associated with acute cerebral ischemia or high-risk transcranial Doppler in a newborn cohort of 395 children with sickle cell anemia

Interleukin-10 haplotypes are not associated with acute cerebral ischemia or high-risk transcranial Doppler in a newborn cohort of 395 children with sickle cell anemia

ABSTRACT Background: The etiology of stroke, a severe complication of sickle cell anemia, involves inflammatory processes. However, the pathogenetic mechanisms are unknown. The aim of this study was to evaluate the influence of interleukin-10 polymorphisms and haplotypes on the risk of acute cerebr...

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Bibliographic Details
Main Authors: André Rolim Belisário, Rahyssa Rodrigues Sales, Nayara Evelin Toledo, Cibele Velloso-Rodrigues, Célia Maria Silva, Marcos Borato Viana
Format: Article
Language:English
Published: Elsevier
Series:Revista Brasileira de Hematologia e Hemoterapia
Subjects:
Sickle cell anemia
Stroke
Polymorphism
Interleukin-10
Transcranial Doppler ultrasound
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842017000200108&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842017000200108&lng=en&tlng=en

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