Quercetin-loaded nanocomposite microspheres for chronologically promoting bone repair via synergistic immunoregulation and osteogenesis

Quercetin-loaded nanocomposite microspheres for chronologically promoting bone repair via synergistic immunoregulation and osteogenesis

Biomaterial implantation for bone defect repair is a complex cascade reaction process, which mainly includes early inflammatory response and subsequent osteogenic repair. In this work, quercetin / nano-hydroxyapatite / poly (glycolide-co-epsilon-caprolactone) (Que/n-HA/PGCL) nanocomposite microspher...

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Bibliographic Details
Main Authors: Chunyu Han, Min Guo, Jianfei Bai, Lanlan Zhao, Liqiang Wang, Wenzhi Song, Peibiao Zhang
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Materials & Design
Subjects:
Drug delivery
Macrophages polarization
BMSC differentiation
Osteoimmunology
Bone regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127522006670

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http://www.sciencedirect.com/science/article/pii/S0264127522006670

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