2.8 Å resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy

2.8 Å resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy

Recent developments in detector hardware and image-processing software have revolutionized single particle cryo-electron microscopy (cryoEM) and led to a wave of near-atomic resolution (typically ∼3.3 Å) reconstructions. Reaching resolutions higher than 3 Å is a prerequisite for structure-based drug...

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Bibliographic Details
Main Authors: Melody G Campbell, David Veesler, Anchi Cheng, Clinton S Potter, Bridget Carragher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-03-01
Series:eLife
Subjects:
electron microscopy
direct detector
image processing
T. acidophilum
Online Access:https://elifesciences.org/articles/06380

Internet

https://elifesciences.org/articles/06380

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