Association of Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) Gene Polymorphisms with Autoimmune Thyroid Disease in Children and Adults: Case-Control Study.

Autoimmune thyroid disease (AITD), including Graves disease (GD) and Hashimoto disease (HD), is an organ-specific autoimmune disease with a strong genetic component. Although the cytotoxic T-lymphocyte-associated protein 4 (CTLA4) polymorphism has been reported to be associated with AITD in adults,...

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Main Authors: Wei-Hsin Ting, Ming-Nan Chien, Fu-Sung Lo, Chao-Hung Wang, Chi-Yu Huang, Chiung-Ling Lin, Wen-Shan Lin, Tzu-Yang Chang, Horng-Woei Yang, Wei-Fang Chen, Ya-Ping Lien, Bi-Wen Cheng, Chao-Hsu Lin, Chia-Ching Chen, Yi-Lei Wu, Chen-Mei Hung, Hsin-Jung Li, Chon-In Chan, Yann-Jinn Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4844099?pdf=render