α1-Microglobulin Protects Against Bleeding-Induced Oxidative Damage in Knee Arthropathies

α1-Microglobulin Protects Against Bleeding-Induced Oxidative Damage in Knee Arthropathies

Knee injury increases the risk of developing knee osteoarthritis (OA). Recent evidence suggests involvement of oxidative stress induced by inflammation and bleeding in the joint. This study investigates the role in this process of α1-microglobulin (A1M), a plasma and tissue antioxidant protein with...

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Bibliographic Details
Main Authors: Staffan Larsson, Bo Åkerström, Magnus Gram, L. Stefan Lohmander, André Struglics
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Physiology
Subjects:
α1-microglobulin
heme
hemoglobin
hemolysis
knee injury
knee osteoarthritis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01596/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01596/full

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