Preventive Action of Beta-Carotene against the Indoxyl Sulfate-Induced Renal Dysfunction in Male Adult Zebrafish via Regulations of Mitochondrial Inflammatory and β-Carotene Oxygenase-2 Actions

Preventive Action of Beta-Carotene against the Indoxyl Sulfate-Induced Renal Dysfunction in Male Adult Zebrafish via Regulations of Mitochondrial Inflammatory and β-Carotene Oxygenase-2 Actions

Indoxyl sulfate (IS) is a metabolic byproduct of indole metabolism. IS readily interacts with the mitochondrial redox metabolism, leading to altered renal function. The β-carotene oxygenase-2 (BCO2) enzyme converts carotenoids to intermediate products. However, the role of β-carotene (BC) in IS-indu...

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Bibliographic Details
Main Authors: Arunachalam Muthuraman, Abu Sadat Md. Sayem, Sakthiganapathi Meenakshisundaram, Nemat Ali, Sheikh F. Ahmad, Abdullah F. AlAsmari, Shamama Nishat, Khian Giap Lim, Yamunna Paramaswaran
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomedicines
Subjects:
adenosine triphosphate
carotenoids
glutathione peroxidase-1
hematoxylin staining
intestinal flora
reduced glutathione
Online Access:https://www.mdpi.com/2227-9059/11/10/2654

Internet

https://www.mdpi.com/2227-9059/11/10/2654

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