Construction of PANoptosis signature: Novel target discovery for prostate cancer immunotherapy

PANoptosis pathway gene sets encompassing pyroptosis, apoptosis, and necroptosis were identified from the MSigDB database. We analyzed the perturbations and crosstalk in the PANoptosis pathway in prostate adenocarcinoma (PRAD), including gene mutation, transcription, methylation, and clinical featur...

Full description

Bibliographic Details
Main Authors: Xianyanling Yi, Jin Li, Xiaonan Zheng, Hang Xu, Dazhou Liao, Tianyi Zhang, Qiang Wei, Hong Li, Jiajie Peng, Jianzhong Ai
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253123001841