Optimizing a three-dimensional spheroid clearing method for the imaging-based evaluation of cardiotoxicity

Background Toxicity evaluation based on two-dimensional cell culture shows differences from clinical results and has the disadvantage of not accurately reflecting cell-to-cell cross-signaling. Since almost all cells in the human body are arranged in a three-dimensional structure and constitute a tis...

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Bibliographic Details
Main Authors: Ji Hye Park, Jaemeun Lee, Sun-Hyun Park, Ki-Suk Kim
Format: Article
Language:English
Published: The Organoid Society 2021-09-01
Series:Organoid
Subjects:
Online Access:http://j-organoid.org/upload/pdf/organoid-2021-1-e7.pdf