Evidence against a human cell-specific role for LRP6 in anthrax toxin entry.

The role of the cellular protein LRP6 in anthrax toxin entry is controversial. Previous studies showed that LRP6 was important for efficient intoxication of human M2182 prostate carcinoma cells but other studies performed with cells from gene-knockout mice demonstrated no role for either LRP6 or the...

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Bibliographic Details
Main Authors: Patricia L Ryan, John A T Young
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2263128?pdf=render