Implications of kappa-casein evolutionary diversity for the self-assembly and aggregation of casein micelles

Milk alpha-, beta- and kappa-casein proteins assemble into casein micelles in breast epithelial cells. The glycomacropeptide (GMP) tails of kappa-casein that extend from the surface of the micelle are key to assembly and aggregation. Aggregation is triggered by stomach pepsin cleavage of GMP from pa...

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Bibliographic Details
Main Authors: Jean Manguy, Denis C. Shields
Format: Article
Language:English
Published: The Royal Society 2019-10-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.190939