Complementarity between miRNA expression analysis and DNA methylation analysis in hrHPV-positive cervical scrapes for the detection of cervical disease

Complementarity between miRNA expression analysis and DNA methylation analysis in hrHPV-positive cervical scrapes for the detection of cervical disease

Cervical screening by high-risk HPV (hrHPV) testing requires additional risk stratification (triage), as most infections are transient and only a subset of hrHPV-positive women harbours clinically relevant disease. Molecular triage markers such as microRNAs (miRNAs) and DNA methylation markers are p...

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Bibliographic Details
Main Authors: Iris Babion, Lise M.A. De Strooper, Roosmarijn Luttmer, Maaike C.G. Bleeker, Chris J.L.M. Meijer, Daniëlle A.M. Heideman, Saskia M. Wilting, Renske D.M. Steenbergen
Format: Article
Language:English
Published: Taylor & Francis Group 2019-06-01
Series:Epigenetics
Subjects:
mirna
methylation
fam19a4
hpv
cervical cancer
cin
scrape
triage
screening
qrt-pcr
Online Access:http://dx.doi.org/10.1080/15592294.2019.1600390

Internet

http://dx.doi.org/10.1080/15592294.2019.1600390

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