Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C-glycoside cleaving enzyme and an O- to C-glycoside isomerase
The C-glycosidic bond that connects the sugar moiety with aglycone is difficult to be broken or made due to its inert nature. The knowledge of C-glycoside breakdown and synthesis is very limited. Recently, the enzyme DgpA/B/C cascade from a human intestinal bacterium PUE was identified to specifical...
Main Authors: | Pengfei He, Sha Wang, Sen Li, Siqi Liu, Shuqi Zhou, Jing Wang, Jiayue Tao, Dongdong Wang, Rufeng Wang, Wenfu Ma |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383522002441 |
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