T Helper 1 and T Helper 2 Cytokines Differentially Modulate Expression of Filaggrin and its Processing Proteases in Human Keratinocytes

T Helper 1 and T Helper 2 Cytokines Differentially Modulate Expression of Filaggrin and its Processing Proteases in Human Keratinocytes

Background: Atopic dermatitis (AD) is characterized by defective skin barrier and imbalance in T helper 1/T helper 2 (Th1/Th2) cytokine expression. Filaggrin (FLG) is the key protein to maintaining skin barrier function. Recent studies indicated that Th1/Th2 cytokines influence FLG expression in ker...

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Bibliographic Details
Main Authors: Zheng-Hong Di, Lei Ma, Rui-Qun Qi, Xiao-Dong Sun, Wei Huo, Li Zhang, Ya-Ni Lyu, Yu-Xiao Hong, Hong-Duo Chen, Xing-Hua Gao
Format: Article
Language:English
Published: Wolters Kluwer 2016-01-01
Series:Chinese Medical Journal
Subjects:
Atopic Dermatitis; Cytokine; Filaggrin; Lymphoepithelial Kazal-type-related Inhibitor; Protease
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=3;spage=295;epage=303;aulast=Di

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http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=3;spage=295;epage=303;aulast=Di

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