Alt a 1 Promotes Allergic Asthma In Vivo Through TLR4-Alveolar Macrophages

Alt a 1 Promotes Allergic Asthma In Vivo Through TLR4-Alveolar Macrophages

The mold Alternaria alternata is one of the main sources of asthma exacerbation, being its major allergen, Alt a 1, indispensable for its development. The main objective of this work was to answer two main questions: 1) can Alt a 1 by itself (without any other context) induce an asthmatic profile in...

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Bibliographic Details
Main Authors: Guadalupe Hernandez-Ramirez, Diego Pazos-Castro, Zulema Gonzalez-Klein, Jose Luis Resuela-Gonzalez, Sergio Fernandez-Bravo, Lucia Palacio-Garcia, Vanesa Esteban, Maria Garrido-Arandia, Jaime Tome-Amat, Araceli Diaz-Perales
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
allergic asthma
Alt a 1
TLR4
alveolar macrophage
mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.877383/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.877383/full

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