The Adhesion GPCR Latrophilin/CIRL Shapes Mechanosensation

G-protein-coupled receptors (GPCRs) are typically regarded as chemosensors that control cellular states in response to soluble extracellular cues. However, the modality of stimuli recognized through adhesion GPCR (aGPCR), the second largest class of the GPCR superfamily, is unresolved. Our study cha...

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Bibliographic Details
Main Authors: Nicole Scholz, Jennifer Gehring, Chonglin Guan, Dmitrij Ljaschenko, Robin Fischer, Vetrivel Lakshmanan, Robert J. Kittel, Tobias Langenhan
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715003836