Brain network hypersensitivity underlies pain crises in sickle cell disease

Brain network hypersensitivity underlies pain crises in sickle cell disease

Abstract Sickle cell disease (SCD) is a genetic disorder causing painful and unpredictable Vaso-occlusive crises (VOCs) through blood vessel blockages. In this study, we propose explosive synchronization (ES) as a novel approach to comprehend the hypersensitivity and occurrence of VOCs in the SCD br...

Full description

Bibliographic Details
Main Authors: Pangyu Joo, Minkyung Kim, Brianna Kish, Vidhya Vijayakrishnan Nair, Yunjie Tong, Ziyue Liu, Andrew R. W. O’Brien, Steven E. Harte, Richard E. Harris, UnCheol Lee, Ying Wang
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-57473-5

Internet

https://doi.org/10.1038/s41598-024-57473-5

Similar Items