Advanced biomanufacturing and evaluation of adeno-associated virus

Advanced biomanufacturing and evaluation of adeno-associated virus

Abstract Recombinant adeno-associated virus (rAAV) has been developed as a safe and effective gene delivery vehicle to treat rare genetic diseases. This study aimed to establish a novel biomanufacturing process to achieve high production and purification of various AAV serotypes (AAV2, 5, DJ, DJ8)....

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Bibliographic Details
Main Authors: Kai Chen, Seulhee Kim, Siying Yang, Tanvi Varadkar, Zhuoxin Zora Zhou, Jiashuai Zhang, Lufang Zhou, Xiaoguang Margaret Liu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Biological Engineering
Subjects:
Adeno-associated virus (AAV)
Biomanufacturing
Bioproduction
Purification
Online Access:https://doi.org/10.1186/s13036-024-00409-4

Internet

https://doi.org/10.1186/s13036-024-00409-4

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