Model for the peptide-free conformation of class II MHC proteins.

Model for the peptide-free conformation of class II MHC proteins.

Major histocompatibility complex proteins are believed to undergo significant conformational changes concomitant with peptide binding, but structural characterization of these changes has remained elusive.Here we use molecular dynamics simulations and experimental probes of protein conformation to i...

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Bibliographic Details
Main Authors: Corrie A Painter, Anthony Cruz, Gustavo E López, Lawrence J Stern, Zarixia Zavala-Ruiz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2408972?pdf=render

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http://europepmc.org/articles/PMC2408972?pdf=render

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