Anti-Fibronectin Aptamer Modifies Blood Clot Pattern and Stimulates Osteogenesis: An Ex Vivo Study

Anti-Fibronectin Aptamer Modifies Blood Clot Pattern and Stimulates Osteogenesis: An Ex Vivo Study

Background: Scaffold (SCA) functionalization with aptamers (APT) provides adsorption of specific bioactive molecules on biomaterial surfaces. The aim of this study was to observe if SCA enriched with anti-fibronectin APT can favor coagulum (PhC) and osteoblasts (OSB) differentiation. Methods: 20 μg...

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Bibliographic Details
Main Authors: Natacha Malu Miranda da Costa, Ludovica Parisi, Benedetta Ghezzi, Lisa Elviri, Sergio Luis Scombatti de Souza, Arthur Belém Novaes, Paulo Tambasco de Oliveira, Guido Maria Macaluso, Daniela Bazan Palioto
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biomimetics
Subjects:
aptamer
blood clot
three dimensional
scaffold
hydrogel
osteogenesis
Online Access:https://www.mdpi.com/2313-7673/8/8/582

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https://www.mdpi.com/2313-7673/8/8/582

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