<i>BRAF<sup>V600E</sup></i> Mutant Allele Frequency (MAF) Influences Melanoma Clinicopathologic Characteristics

<i>BRAF<sup>V600E</sup></i> Mutant Allele Frequency (MAF) Influences Melanoma Clinicopathologic Characteristics

Background: Cutaneous melanoma shows high variability regarding clinicopathological presentation, evolution and prognosis. Methods: Next generation sequencing was performed to analyze hotspot mutations in different areas of primary melanomas (MMp) and their paired metastases. Clinicopathological fea...

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Bibliographic Details
Main Authors: Xavier Soria, Felip Vilardell, Óscar Maiques, Carla Barceló, Pol Sisó, Inés de la Rosa, Ana Velasco, Dolors Cuevas, Maria Santacana, Sònia Gatius, Xavier Matías-Guiu, Alberto Rodrigo, Anna Macià, Rosa M. Martí
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
melanoma
<i>BRAF<sup>V600E</sup></i>
next generation sequencing
mutant allele frequency
intratumor heterogeneity
Online Access:https://www.mdpi.com/2072-6694/13/20/5073

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https://www.mdpi.com/2072-6694/13/20/5073

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