Regulation of Protein-Induced Apoptosis and Autophagy in Human Hepatocytes Treated with Metformin and Paclitaxel In Silico and In Vitro

Regulation of Protein-Induced Apoptosis and Autophagy in Human Hepatocytes Treated with Metformin and Paclitaxel In Silico and In Vitro

Metformin and paclitaxel therapy offer promising outcomes in the treatment of liver cancer. Combining paclitaxel with metformin enhances treatment effectiveness and mitigates the adverse effects associated with paclitaxel alone. This study explored the anticancer properties of metformin and paclitax...

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Bibliographic Details
Main Authors: Norah Saeed Al-Zahrani, Mazin Abdulaziz Zamzami, Mohammed A. Baghdadi, Afnan H. El-Gowily, Ehab M. M. Ali
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomedicines
Subjects:
metformin
paclitaxel
AMPK-α
apoptosis
autophagy
Online Access:https://www.mdpi.com/2227-9059/11/10/2688

Internet

https://www.mdpi.com/2227-9059/11/10/2688

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