Overexpression of SCAP inhibits autophagy and promotes lipid accumulation in vascular smooth muscle cells

Overexpression of SCAP inhibits autophagy and promotes lipid accumulation in vascular smooth muscle cells

Objective To determine the effect of sterol regulatory element binding proteins cleavage activating protein (SCAP) on foam cell formation in vascular smooth muscle cells (VSMCs). Methods LV-SCAP were constructed with LV-SCAP, and LV-Control group served as control. The expression of SCAP and its do...

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Bibliographic Details
Main Authors: RAO Yuhan, LI Danyang, HOU Xiaoli, YAO Yincheng, SU Yu
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2022-05-01
Series:Di-san junyi daxue xuebao
Subjects:
sterol regulatory element binding proteins cleavage activating protein
vascular smooth muscle cells
autophagy
ampk-mtor pathway
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202110042.htm

Internet

http://aammt.tmmu.edu.cn/Upload/rhtml/202110042.htm

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