Meta-regression of randomized control trials with antithrombotics: weak correlation between net clinical benefit and all cause-mortality

Meta-regression of randomized control trials with antithrombotics: weak correlation between net clinical benefit and all cause-mortality

Abstract This study aimed to explore the validity of the use of the net clinical benefit (NCB), i.e. the sum of major bleeding and thrombotic events, as a potential surrogate for all-cause mortality in clinical trials assessing antithrombotics. Published randomized controlled trials testing anticoag...

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Bibliographic Details
Main Authors: Roubi Kilo, Silvy Laporte, Rama Arab, Sabine Mainbourg, Steeve Provencher, Guillaume Grenet, Laurent Bertoletti, Laurent Villeneuve, Michel Cucherat, Jean-Christophe Lega, META-EMBOL Group
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94160-1

Internet

https://doi.org/10.1038/s41598-021-94160-1

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