Protection of p53 wild type cells from taxol by nutlin-3 in the combined lung cancer treatment

<p>Abstract</p> <p>Background</p> <p>Mutations within the tumor suppressor <it>TP53 </it>gene are one of the most common genetic alterations present at high frequency in human tumors and have been shown to be associated with resistance to radio-chemotherapy....

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Bibliographic Details
Main Authors: Abolmaali Nasreddin D, Tokalov Sergey V
Format: Article
Language:English
Published: BMC 2010-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/57