Creation of targeted inversion mutations in plants using an RNA-guided endonuclease

Inversions are DNA rearrangements that are essential for plant gene evolution and adaptation to environmental changes. We demonstrate the creation of targeted inversions and previously reported targeted deletion mutations via delivery of a pair of RNA-guided endonucleases (RGENs) of CRISPR/Cas9. The...

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Bibliographic Details
Main Authors: Congsheng Zhang, Changlin Liu, Jianfeng Weng, Beijiu Cheng, Fang Liu, Xinhai Li, Chuanxiao Xie
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2017-02-01
Series:Crop Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214514116301064