MPST deficiency promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via AKT

MPST deficiency promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via AKT

Background & aims: Excessive inflammatory responses and oxidative stress are considered the main characteristics of inflammatory bowel disease (IBD). Endogenous hydrogen sulfide (H2S) has been reported to show anti-inflammatory activity in IBD. The main aim of this study was to explore the r...

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Bibliographic Details
Main Authors: Jie Zhang, Li Cen, Xiaofen Zhang, Chenxi Tang, Yishu Chen, Yuwei Zhang, Mengli Yu, Chao Lu, Meng Li, Sha Li, Bingru Lin, Tiantian Zhang, Xin Song, Chaohui Yu, Hao Wu, Zhe Shen
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Redox Biology
Subjects:
3-Mercaptopyruvate sulfurtransferase
Epithelial cell
Hydrogen sulfide
Anti-Apoptotic protein kinase
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722002415

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http://www.sciencedirect.com/science/article/pii/S2213231722002415

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