Elevated MACC1 Expression in Colorectal Cancer Is Driven by Chromosomal Instability and Is Associated with Molecular Subtype and Worse Patient Survival

Elevated MACC1 Expression in Colorectal Cancer Is Driven by Chromosomal Instability and Is Associated with Molecular Subtype and Worse Patient Survival

Metastasis-Associated in Colon Cancer 1 (<i>MACC1</i>) is a strong prognostic biomarker inducing proliferation, migration, invasiveness, and metastasis of cancer cells. The context of <i>MACC1</i> dysregulation in cancers is, however, still poorly understood. Here, we investi...

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Bibliographic Details
Main Authors: Vincent Vuaroqueaux, Alexandra Musch, Dennis Kobelt, Thomas Risch, Pia Herrmann, Susen Burock, Anne-Lise Peille, Marie-Laure Yaspo, Heinz-Herbert Fiebig, Ulrike Stein
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
CRC
MACC1
gene copy number alteration
gene expression
survival
Online Access:https://www.mdpi.com/2072-6694/14/7/1749

Internet

https://www.mdpi.com/2072-6694/14/7/1749

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