Hypertonic saline and pentoxifylline enhance survival, reducing apoptosis and oxidative stress in a rat model of strangulated closed loop small bowel obstruction

Hypertonic saline and pentoxifylline enhance survival, reducing apoptosis and oxidative stress in a rat model of strangulated closed loop small bowel obstruction

OBJECTIVES: Intestinal obstruction has a high mortality rate when therapeutic treatment is delayed. Resuscitation in intestinal obstruction requires a large volume of fluid, and fluid combinations have been studied. Therefore, we evaluated the effects of hypertonic saline solution (HS) with pentoxif...

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Bibliographic Details
Main Authors: Gustavo Scapini, Roberto Rasslan, Natalie Chaves Cayuela, Miguel Angelo Goes, Marcia Kiyomi Koike, Edivaldo Massazo Utiyama, Edna Frasson de Souza Montero, Samir Rasslan
Format: Article
Language:English
Published: Elsevier España
Series:Clinics
Subjects:
Apoptosis
Hypertonic Saline
Intestinal Obstruction
Oxidative Stress
Pentoxifylline
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322019000100236&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322019000100236&lng=en&tlng=en

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