Exploration of the quantitative Structure-Activity relationships for predicting Cyclooxygenase-2 inhibition bioactivity by Machine learning approaches
Cyclooxygenase-2 (COX-2) overexpression in many humans plays a key role in carcinogenic and inflammation-associated diseases. Several therapeutic and pharmaceutic drugs have been developed but some of them either lack the potency to control the COX-2 related diseases or promote unwanted side effects...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-01-01
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Series: | Results in Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715621001776 |