A detachable coating of cholesterol-anchored PEG improves tumor targeting of cell-penetrating peptide-modified liposomes

A detachable coating of cholesterol-anchored PEG improves tumor targeting of cell-penetrating peptide-modified liposomes

Cell-penetrating peptides (CPPs) have been widely used to enhance the membrane translocation of various carriers for many years, but the non-specificity of CPPs seriously limits their utility in vivo. In this study, cholesterol-anchored, reduction-sensitive PEG (first synthesized by our laboratory)...

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Bibliographic Details
Main Authors: Jie Tang, Li Zhang, Han Fu, Qifang Kuang, Huile Gao, Zhirong Zhang, Qin He
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Cell penetrating peptide
Reduction-sensitive PEG
Tumor targeting
Cholesterol
Liposome
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383513001093

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http://www.sciencedirect.com/science/article/pii/S2211383513001093

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