Mutation load decreases with haplotype age in wild Soay sheep

Mutation load decreases with haplotype age in wild Soay sheep

Abstract Runs of homozygosity (ROH) are pervasive in diploid genomes and expose the effects of deleterious recessive mutations, but how exactly these regions contribute to variation in fitness remains unclear. Here, we combined empirical analyses and simulations to explore the deleterious effects of...

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Bibliographic Details
Main Authors: Martin A. Stoffel, Susan E. Johnston, Jill G. Pilkington, Josephine M. Pemberton
Format: Article
Language:English
Published: Oxford University Press 2021-06-01
Series:Evolution Letters
Subjects:
Deleterious mutation
fitness
inbreeding depression
ROH
runs of homozygosity
survival
Online Access:https://doi.org/10.1002/evl3.229

Internet

https://doi.org/10.1002/evl3.229

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