Probing the communication patterns of different chondrocyte subtypes in osteoarthritis at the single cell level using pattern recognition and manifold learning

Abstract The patterns of communication among different chondrocyte subtypes in human cartilage degeneration and regeneration help us understand the microenvironment of osteoarthritis and optimize cell-targeted therapies. Here, a single-cell transcriptome dataset of chondrocytes is used to explore th...

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Bibliographic Details
Main Authors: Jiajian Wang, Caihong Liu, Litao Yang, Huixiong Chen, Mingqi Zheng, Yanbin Wan, Xiongxin Hong, Sidi Li, Jing Han, Ruibin Luo, Xing Wan, Jian V. Zhang, Ruihuan Xu
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41874-z