Evaluation of the immunogenicity and safety of different doses and formulations of a broad spectrum influenza vaccine (FLU-v) developed by SEEK: study protocol for a single-center, randomized, double-blind and placebo-controlled clinical phase IIb trial

Evaluation of the immunogenicity and safety of different doses and formulations of a broad spectrum influenza vaccine (FLU-v) developed by SEEK: study protocol for a single-center, randomized, double-blind and placebo-controlled clinical phase IIb trial

Abstract Background Current influenza vaccines, based on antibodies against surface antigens, are unable to provide protection against newly emerging virus strains which differ from the vaccine strains. Therefore the population has to be re-vaccinated annually. It is thus important to develop vaccin...

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Bibliographic Details
Main Authors: Eva van Doorn, Olga Pleguezuelos, Heng Liu, Ana Fernandez, Robin Bannister, Gregory Stoloff, Fredrik Oftung, Stephen Norley, Anke Huckriede, Henderik W. Frijlink, Eelko Hak
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Infectious Diseases
Subjects:
Broadly protection
Clinical trial
CMI
FLU-v
Influenza
Universal
Online Access:http://link.springer.com/article/10.1186/s12879-017-2341-9

Internet

http://link.springer.com/article/10.1186/s12879-017-2341-9

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