Protein–Protein Interaction between Surfactant Protein D and DC-SIGN via C-Type Lectin Domain Can Suppress HIV-1 Transfer

Protein–Protein Interaction between Surfactant Protein D and DC-SIGN via C-Type Lectin Domain Can Suppress HIV-1 Transfer

Surfactant protein D (SP-D) is a soluble C-type lectin, belonging to the collectin (collagen-containing calcium-dependent lectin) family, which acts as an innate immune pattern recognition molecule in the lungs at other mucosal surfaces. Immune regulation and surfactant homeostasis are salient funct...

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Bibliographic Details
Main Authors: Eswari Dodagatta-Marri, Daniel A. Mitchell, Hrishikesh Pandit, Archana Sonawani, Valarmathy Murugaiah, Susan Idicula-Thomas, Béatrice Nal, Maha M. Al-Mozaini, Anuvinder Kaur, Taruna Madan, Uday Kishore
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Immunology
Subjects:
surfactant protein D
DC-SIGN
HIV-1 infection
protein–protein interactions
gp120
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00834/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00834/full

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